Sodium 1-hexanesulfonate
Product name: Sodium 1-hexanesulfonate
Synonym(s): Hexane-1-sulfonic acid sodium salt
CAS Number: 2832-45-3
Introduction
| assay | ≥99% (acidimetric) |
| technique(s) | ion pair chromatography: suitable |
| loss | ≤2 loss on drying, 120°C; 4h; vacuum |
| transmittance | 200 nm, ≥70% 220 nm, ≥90% 250 nm, ≥98% (0.005 M; 1 cm in H2O) |
| pH | 5.5-7.5 (20 °C, 100 g/L in H2O) |
| suitability | passes test for identity (IR) |
| Storage temp. | 15-25°C |
| SMILES string | [Na+].[S](=O)(=O)([O-])CCCCCC |
| InChI | 1S/C6H14O3S.Na/c1-2-3-4-5-6-10(7,8)9;/h2-6H2,1H3,(H,7,8,9);/q;+1/p-1 |
| InChI key | QWSZRRAAFHGKCH-UHFFFAOYSA-M |
General description
Hexane-1-sulfonicacid sodium salt is a commonly used ion-pair reagent in ion-pairchromatography. It is used as an ion-pair reagent to generate neutralequilibrium with the analytes, leading to increased retention and improvedseparation during the chromatographic analysis.
Application
Hexane-1-sulfonic acid sodium salt can be used as a:
Part of the mobile phase composition in an HPLC stability-indicating method for the simultaneous determination of water-soluble vitamins and preservatives.
Buffer component in a reverse-phase ultra-performance liquid chromatography (UPLC) method for the simultaneous determination of Sitagliptin phosphate monohydrate and Metformin hydrochloride in pharmaceutical dosage forms.
