Sodium 1-heptanesulfonate
Product name: Sodium 1-heptanesulfonate
Synonym(s): 1-Heptanesulfonic acid sodium salt
CAS Number: 22767-50-6
Introduction
| biological source | synthetic (oragnic) |
| Quality Level | 100 |
| description | anionic |
| form | powder |
| mol wt | 202.25 g/mol |
| technique(s) | HPLC: suitable LC/MS: suitable |
| impurities | <2.0% water (Karl Fischer) |
| mp | 300 °C (572 °F) |
| solubility | H2O: ≥100 mg/mL |
| cation traces | Na: 10.8-12.0 % (w/v) (anhydrous) |
| SMILES string | [Na+].CCCCCCCS([O-])(=O)=O |
| InChI | 1S/C7H16O3S.Na/c1-2-3-4-5-6-7-11(8,9)10;/h2-7H2,1H3,(H,8,9,10);/q;+1/p-1 |
| InChI key | REFMEZARFCPESH-UHFFFAOYSA-M |
General description
Sodium 1-heptanesulfonate belongs to the sodium alkylsulfonate group of surfactants. It has a -SO?3 head group with sodium and an alkyl chain attached to the head group. Sodium 1-heptanesulfonate has a critical micelle concentration value of 0.302 mol/dm3.
Sodium 1-heptanesulfonate, also known as sodium heptanesulfonate, is a versatile compound commonly used in lab experiments and biochemical research. It acts as an ion-pairing agent, surfactant, and buffer, playing a crucial role in various applications. In biochemistry, it helps with tasks like protein purification and nucleic acid separation by reducing surface tension for better mixing. It also serves as a chelating agent for metal ion analysis and acts as a buffer in biological experiments. Sodium 1-heptanesulfonate is a preferred choice in HPLC and high-performance capillary electrophoresis analyses, aiding in the separation of positively charged analytes in both organic and inorganic compounds, from pharmaceuticals to peptide research.
Application
Ion-pairing reagent for HPLC, including analyses of peptides and proteins.
Sodium 1-heptanesulfonate has been used as a component of the mobile phase buffer for preequilibration of high performance liquid chromatography column.
Biochem/physiol Actions
Sodium 1-heptanesulfonate serves as an ion-pairing reagent for analysis of epinephrine and norepinephrine in ion-pairing chromatography (IPC).
