Specialty Chemicals

Sodium Pentanesulfonate (CAS 22767-49-3) :‌

• ‌Chemical Name‌: Sodium pentanesulfonate
• ‌CAS Number‌: 22767-49-3
• ‌Molecular Formula‌: C₅H₁₁O₃SNa (anhydrous), or C₅H₁₃NaO₃S (monohydrate commonly supplied)
• ‌Molecular Weight‌: 174.19 g/mol (anhydrous), 176.21 g/mol (monohydrate)
• ‌Appearance‌: White to off-white crystalline powder, odorless
• ‌Melting Point‌: ≥300 °C (decomposes)
• ‌Solubility‌: Freely soluble in water, forming a clear, colorless solution; solubility >500 g/L at 25 °C
• ‌UV Cutoff‌: ~210 nm, suitable for HPLC detection with UV detection systems
• ‌Purity‌: Typically ≥98% (HPLC or titration grade); high-purity grades (≥99%) available for chromatographic applications
• ‌Hygroscopicity‌: Slightly hygroscopic, store in sealed containers
• ‌Stability‌: Stable under normal temperature and pressure; avoid strong oxidizing agents
• ‌Applications‌:
  • Widely used as an ion-pair reagent in reversed-phase HPLC (RP-HPLC) for the separation of cationic compounds such as amines, peptides, and antibiotics.
  • Acts as an anionic surfactant in formulation development with low toxicity and high water solubility.
  • Compatible with mass spectrometry (MS) when used in low concentrations.
• ‌Storage‌: Store in a cool, dry, well-ventilated area. Recommended to keep at 2–8 °C for long-term stability. Protect from moisture and light.
• ‌Safety Information‌:
  • Generally considered low toxicity; however, avoid inhalation, skin contact, and ingestion.
  • Use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat during handling.
  • No significant acute hazards reported, but follow standard laboratory safety practices.